Meridia 15 mg Vertaxpharma

Meridia (sibutramine/fenfluramine) is a prescription medicine used to help obese people lose and maintain weight. Meridia works by suppressing your appetite and reducing the absorption of fat from your food. Meridia should only be used for short periods of time.

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Cena od 55,00 €

What is Meridia 15 mg?

Meridia 15 mg contained sibutramine, an appetite-suppressant originally approved for obesity treatment. Sibutramine acted on the central nervous system, increasing levels of serotonin and noradrenaline, leading to reduced hunger and enhanced satiety.

Despite its early popularity, clinical trials later revealed serious cardiovascular risks, which led to its global withdrawal.

Ingredients of Meridia 15 mg

Active ingredient: Sibutramine hydrochloride monohydrate
Excipients include:
- microcrystalline cellulose
- lactose monohydrate
- magnesium stearate
- gelatin
- capsule colorants

How does sibutramine work?

Sibutramine works by inhibiting the reuptake of:

serotonin
noradrenaline
dopamine (partially)

This results in:

appetite reduction
earlier satiety
mild increase in metabolic rate

Cardiovascular risks:

The SCOUT clinical trial confirmed that sibutramine significantly increases the risk of: